Barbara Van Rooyan is a mother from Virginia whose son, Patrick, becomes a victim of the opioid epidemic at age 24. She becomes a vocal advocate against OxyContin, petitioning the FDA to recall it. Along the way, she joins forces with fellow activists like Art Van Zee and Sister Beth. Staffers at the FDA become familiar with Van Rooyan due to her frequent calls. Eventually, the FDA makes good on what she asks for in her petitions, but the response is too little too late.