is
Hazel and
Augustus’ mutual friend. A rare form of eye cancer blinds
Isaac, and his situation leads him to cynicism and anger. After being blinded, his girlfriend,
Monica, leaves him, which is a devastating event in Isaac’s life. His character shows the way in which typical coming of age experiences, like the end of a young relationship, is particularly difficult for the young characters living with cancer. Isaac’s name also carries a religious connotation, as the biblical character Isaac also goes blind.