In the last two lines, the poem makes a surprising shift. Here, the speaker addresses "My heart" and "My love" directly:
My heart, have you no wisdom thus to despair?
My love, my love, my love, why have you left me alone?
This important moment implies that this nightmarish invasion is really a product of the speaker's emotional distress. These apostrophes emphasize the speaker's solitude: their heart cannot answer because it's part of the speaker, and the lover won't respond because they've already "left" (they've either broken things off with the speaker or died), leaving the speaker in turmoil.
Note that the speaker is also personifying their own heart here, treating it as an entity that can act independently of the speaker's will. This emphasizes how out of control the speaker's emotions feel; they can't stop their "heart" from despairing. That the speaker calls out to their own heart reflects their sense of fragmentation and perhaps some self-loathing. The speaker feels like they should know better than to fall into the trap of heartbreak.
The call-out to the speaker's love, meanwhile, happens not once, but three times in a row. This conveys the speaker's desperation.
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