Charles “Boss” Kettering was an American inventor and businessman who headed the research department of General Motors from 1920 to 1947. Mona calls Kettering the greatest “public health villain” of all time because of his insistence that leaded gasoline was safe to use. Kettering’s insistence that lead was a benign substance—when, in reality, it is one of the most dangerous neurotoxins in existence—resulted in thousands of deaths.